Bacterial peptidoglycan (murein) hydrolases
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چکیده
منابع مشابه
Bacterial peptidoglycan (murein) hydrolases.
Most bacteria have multiple peptidoglycan hydrolases capable of cleaving covalent bonds in peptidoglycan sacculi or its fragments. An overview of the different classes of peptidoglycan hydrolases and their cleavage sites is provided. The physiological functions of these enzymes include the regulation of cell wall growth, the turnover of peptidoglycan during growth, the separation of daughter ce...
متن کاملBinding site-shaped repeated sequences of bacterial wall peptidoglycan hydrolases.
The non-catalytic C-terminal regions of the N-acetylmuramidase (lysozyme) of Clostridium acetobutylicum and N-acetylmuramoyl(D-lactyl)-L-alanine amidases CwlA of Bacillus subtilis, ORFL3 and CwlL of Bacillus licheniformis were previously reported to have similarities with the amino acid sequence of the non-catalytic N-terminal module of the Streptomyces albus G Zn DD-peptidase. This peptidase i...
متن کاملIn vitro Destruction of Streptococcus pneumoniae Biofilms 3 with Bacterial and Phage Peptidoglycan Hydrolases
1 2 In vitro Destruction of Streptococcus pneumoniae Biofilms 3 with Bacterial and Phage Peptidoglycan Hydrolases 4 5 Mirian Domenech, Ernesto García*, and Miriam Moscoso 6 7 Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones 8 Científicas, Ramiro de Maeztu, 9, 28040 Madrid, and CIBER de Enfermedades 9 Respiratorias (CIBERES),† Spain 10 11 12 Running title: Disintegration...
متن کاملIn vitro destruction of Streptococcus pneumoniae biofilms with bacterial and phage peptidoglycan hydrolases.
Host- and phage-coded cell wall hydrolases have been used to fight Streptococcus pneumoniae growing as planktonic cells in vitro as well as in animal models. Until now, however, the usefulness of these enzymes in biofilm-grown pneumococci has gone untested. The antipneumococcal activity of different cell wall hydrolases produced by S. pneumoniae and a number of its phages was examined in an in ...
متن کاملSpecialized Peptidoglycan Hydrolases Sculpt the Intra-bacterial Niche of Predatory Bdellovibrio and Increase Population Fitness
Bdellovibrio are predatory bacteria that have evolved to invade virtually all gram-negative bacteria, including many prominent pathogens. Upon invasion, prey bacteria become rounded up into an osmotically stable niche for the Bdellovibrio, preventing further superinfection and allowing Bdellovibrio to replicate inside without competition, killing the prey bacterium and degrading its contents. H...
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ژورنال
عنوان ژورنال: FEMS Microbiology Reviews
سال: 2008
ISSN: 1574-6976
DOI: 10.1111/j.1574-6976.2007.00099.x